Matchups › Diana › vs Syndra

Diana vs Syndra

DianaYOU · MID
SyndraENEMY · MID
VS
Favors youPre-6 EasyPost-6 EasyTake Ignite

How to play it

Dodge her stun (E)
Her E is her one kill setup: avoid the stun by walking side to side, never straight toward or away from her.
Your trade window
Take heavy trades and lead with E so she can't react: she stays squishy all game, so keep hunting 100-0s.
Q before you E
Land Q before you E in: the mark resets your E, so if she knocks you back without stunning you, you can dash right back on.
Never walk straight in or straight out when she can E: move side to side or you eat the stun.
Runes
DOMINATIONDOMINATION
Electrocute
Dark Harvest
Hail of Blades
Cheap Shot
Taste of Blood
Sudden Impact
Sixth Sense
Grisly Mementos
Deep Ward
Treasure Hunter
Relentless Hunter
Ultimate Hunter
RESOLVERESOLVE
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
16.14 Emerald+ - 54% WR - 1.4k games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
MAXQQWWEE
Diana · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Diana vs Syndra in Mid lane is a favourable lane on patch 26.17. The one thing to respect: her E is her only hard CC, sidestep it, never walk straight in or straight out.

Diana matchup data compiled from the contributions of Diana OTPsLeague of Legends assets © Riot Games (Data Dragon).