Matchups › Cassiopeia › vs Vladimir

Cassiopeia vs Vladimir

CassiopeiaYOU · MID
VladimirENEMY · MID
VS
Favors youPre-6 EasyPost-6 EasyTake Teleport

How to play it

Dodge empowered Q
Stay outside 600 range of his empowered Q's: they deal far more damage and healing, so only eat one if you're committing to an extended fight.
Space with your range
His E is only 600 range and blocked by minions: poke him with your full kit from outside it and he can't answer.
Bait his pool
His W pool is a 28s cooldown and he has far less outplay while it's down: W him first and he stays grounded and slowed inside it.
Never sit inside 600 range of his empowered Q: that's the one thing that lets him out-trade you.
Runes
SORCERYSORCERY
Summon Aery
Arcane Comet
Stormraider's Surge
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
PRECISIONPRECISION
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
TeleportTELEPORT
Items
Start
Core
16.14 Emerald+ - 50% WR - 354 games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
MAXEEQQWW
Cassiopeia · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Cassiopeia vs Vladimir in Mid lane is a favourable lane on patch 26.17. The one thing to respect: his empowered Q's, stay outside 600 range of them; they hit and heal for far more than his basic Transfusion.

Cassiopeia matchup data compiled from the contributions of Cassiopeia OTP mainsLeague of Legends assets © Riot Games (Data Dragon).