She monster-scales, so land your wincondition before her 3-4 item spike.

Matchups › Akali › vs Syndra

Akali vs Syndra

YOU · MID

ENEMY · MID

Skill matchupPre-6 MediumPost-6 MediumTake Ignite

How to play it

✓

Track her E

Her E is her whole answer to you: its cooldown is your only real timer, so bait it before committing.

✓

Punish her step-up

Find the moment she uses E and walks up too far: then you can ult her and kill from full HP.

✓

Deny her stacks

Stop her stacking off cannons and off you: every stack also refunds her mana.

Never let her free-stack off cannons and off you.

Runes

DOMINATION

RESOLVE

SHARDS

Spells

FLASH

IGNITE

Items

Start

Core

→

16.14 Emerald+ - 51% WR - 2.2k games

Skill order

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Q			Q	Q		Q	Q
		W											W	W		W	W
	E							E	E		E	E
					R					R					R

MAX

Q→

E→

Akali · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Akali vs Syndra in Mid lane is a skill matchup on patch 26.17. The one thing to respect: Her E cooldown is everything, it's her stun and her escape, so bait it before you dive.